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The final stretch of the Mount Baker Highway will not reopen until likely June if weather patterns follow previous trends.
The work is part of a project to improve a 10-mile stretch of the highway between Blaine and the Nooksack River.
Investigating troopers found that one of the drivers had failed to negotiate a curve when they took the northbound off-ramp to Main Street and went airborne.
Bellingham Public Schools says the bus was turning onto Lakeway Drive when the collision occurred.
Drivers should expect one-lane closures with flaggers guiding traffic during construction.
Crews will be clearing catch basins and ditches, removing hazardous trees and making guardrail and shoulder repairs as part of early winter maintenance.
The semi flipped on its side just after 9 a.m. Wednesday morning.
Samish Park was also closed as part of the bridge work, and will remain closed until further notice.
The Mt. Baker Hill Climb starts at Snowater Road near Chair 9 and takes cyclists on a 22.4-mile ride along the Nooksack River before climbing up to Artist Point on Mount Baker with a total elevation gain of 4,482 ft.
WSDOT says that construction will begin on Tuesday night for the southbound lanes in Ferndale.